The amoxicillin belongs to the group of medicines called penicillinsand is the active principle of antibiotics. It is used to treat certain infections caused by bacteria, such as pneumonia and bronchitis (infection of the airways leading to the lungs); as well as infections of the ears, nose, throat, urinary tract and skin.
essentially act slow the growth of bacteria. This is why, as experts always remind us, it is important to use antibiotics only when necessary. That is to put an end to the diseases that cause the bacteria. If used improperly, there is a risk that in the future these drugs do not have the effect they should since the body will present resistance to them.
However, as with other drugs, amoxicillin may have Side effects in those who consume it. This does not mean that everyone taking this drug will get it; in fact, many of them (the most serious) They are very rare. Also, if consumed under medical supervision there should be no problem.
The Spanish Agency for Medicines and Health Products (AEMPS) published on its website all the the possible side effects of this medicine according to their frequency, which also appears in the prospectus thereof.
Reactions that may be common
Some reactions that appear in one in 10 patients are there rash, nausea and diarrhea. Less common still (occurring in one in 100 people) are the vomiting and mildly itchy rash (round, pink or red piping); as good as swollen areas that look like blisters on the forearms, legs, palms, hands or feet.
Very rare reactions
These are the effects that can happen to one in 10,000 people:
- candidiasis (yeast infection in the vagina, mouth or skin folds).
- problems of kidney.
- attacks epileptic (seizures), which have occurred mainly in patients on high doses or with kidney problems.
- dizziness.
- hyperactivity.
- crystals in urine, which may appear as cloudy urine or difficulty or discomfort during urination. Drinking plenty of fluids helps reduce the risk of these symptoms.
- The language it may change color to yellow, brown or black and may have a hairy appearance.
- If an excessive breakdown of blood cells occurs, it can cause a type of anemia. Signs of this include: fatigue, headache, shortness of breath, dizziness, paleness and yellowing of the skin and whites of the eyes.
- low number of white blood cells.
- Low number of cells involved in blood clotting.
- Blood can also take longer than normal to clot. This can be noticed if your nose starts bleeding or if you cut yourself and the bleeding is hard to stop.
Very serious rare reactions to amoxicillin according to the Spanish Agency for Medicines and Health Products

These Side effects caused by the consumption of amoxicillin also appear very exceptionally, only in one in 10,000 patients. However, if you start feeling any of them, you should stop taking the medicine immediately and see a doctor. These symptoms may appear during treatment or even several weeks later.
- Allergic reactions, the signs of which may include itchy skin or a rash, swelling of the face, lips, tongue, body, or difficulty breathing. These could be fallen down and, only on a few occasions, deaths have occurred.
- Skin rash or flat red round spots like the point of a pin below the surface of the skin or bruises on the skin. This is caused by the inflammation of blood vessel walls following an allergic reaction. May be associated with joint pain (arthritis) and problems with kidneys.
- A delayed allergic reaction may also occur after 7 and 12 days after taking this Medication. Some signs include: rash, fever, joint pain, and enlarged lymph nodes, especially under the arms.
- A skin reaction called “Erythema multiforme”. This may develop: itchy purple or red welts on the skin, especially on the palms or soles of the feet; bulging swollen areas on the skin; soft tissues on the surface of the mouth, eyes and genitals. You can also suffer fever and being very tired.
- Others severe skin reactions These can be changes in skin color, lumps under the skin, blisters, pustules, peeling, redness, pain, itching or flaking. They may be accompanied by fever, headache and body aches.
- flu-like symptoms with rash, fever, swollen glands and abnormal blood test results (such as increased white blood cells – eosinophilia – and elevated liver enzymes).
- Fever, chills, sore throat or other signs of infection, as well as easy bruising. These may be signs of a problem with your blood cells.
- reaction of Jarisch-Herxheimerthat occurs during amoxicillin treatment for Alzheimer’s disease Lyme and causes fever, chills, headaches, and muscle and skin rashes.
- Inflammation of the large intestine (colon) with diarrhea (sometimes bloody), pain and fever.
- Serious side effects may also appear in liver. These are mostly associated with patients on long-term treatment, males, and older ages.