CIBERINFEC promotes a new project to assess the clinical and microbiological impact of monkeypox

CIBER Infectious Diseases Area Groups (CIBERINFEC) promoted a multicenter study to assess the clinical and microbiological impact of the monkeypox virus outbreak on patients.

The project, coordinated by Mª Paz Sánchez-Seco and Jesús Oteo, at the ISCIII National Microbiology Center, will see the participation of numerous groups from CIBER, from the field of infectious diseases, from CIBERINFEC, as well as from the field of epidemiology and public health, CIBERESP.

The project aims to develop harmonized detection protocols, quality controls; identify clusters or chains of transmission; carry out a clinical evolution of the cases according to the microbiological variables; know the clinical impact in patients at risk; carry out an evolutionary and viability study of the virus excreted in viruses in different fluids, as well as the response of immunomodulators, among others.

It is structured in five work modules: WP1 will be dedicated to coordination, dissemination and translation; WP2 is led by Vicente Estrada (Hospital Clínico San Carlos, Madrid) and José Luis Blanco (Hospital Clinic de Barcelona) where they will address clinical research; WP3 will work on epidemiological research and will be coordinated by Pere Godoy (CIBERESP-Universitat Barcelona) and Asunción Díaz Franco (National Epidemiology Center-ISCIII). WP4 will focus on the virological research approach and will be coordinated by Anabel Negredo (National Center for Microbiology-ISCIII) and Julián Pardo (University of Zaragoza); Finally, WP5 will deal with the harmonization of detection and control procedures under the coordination of Miguel Martínez Yoldi (Clinical Hospital of Barcelona) and Federico García García (San Cecilio Hospital of Granada).

The CIBERINFEC research initiative responds to one of the most important current public health needs since, since May of this year, multiple cases of this disease have been reported in non-endemic countries. In Spain, according to the latest data from the Ministry of Health, through the National Epidemiological Surveillance Network (RENAVE), a total of 2,447 cases of monkeypox have been confirmed.

In addition, CIBERINFEC is progressing in a collaboration with the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) to work on this and other topics of interest to both.

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