when and how can it be stopped

People walking on the street.

“Cutting the transmission of Covid-19 will take years. because it is a very difficult procedure, the only thing we can do is protect the population,” Vicente Larraga, from the Margarita Salas Biological Research Center (CIB-CSIC), insists so much on the possibility that science can reduce the community infectivity capacity of SARS-CoV-2. A feeling that she shares with her colleague Sonia Zuñiga, who places her hope in the arrival of intranasal covid vaccines: “It is the best solution and what would cut the transmissionbut they are not going to happen in the near future”.

Concretely, the CIB-CSIC virologist predicts that the first intranasal vaccine will arrive as soon as possible at the end of 2023. “For this fall it is impossible, even if the most advanced vaccines had results, it would still take some time to arrive .” permission. Maybe end of 2023 one could be available if good results are obtained. Those from China and India, based on adenoviruses, are the most advanced, while there is another one based on an inactivated virus, also quite advanced, but which will have problems with approval, because it is a technique usually avoided in human health. .

In addition, Zuñiga points out that “many scientists” have worked from the beginning on the development of intranasal vaccines “because we knew it was the only way to cut the transmission. As a result of this initiative, it seven different intranasal vaccines in the world that are already in clinical trials and three of them are in phase three. “These will give us an idea of ​​safety and effectiveness, but we have to keep in mind that they take longer to develop because they don’tmuch more security testing is needed because this is not the usual method.


Global vaccination coverage, key to the transmission of covid

Covid-19 mutations are one of the main issues fueling a rebound in community transmission, and one of the causes behind these new variants is the lack of vaccination coverage in the poorest countries. “We have billions of people left who are not vaccinated, it is a very slow and expensive process. Moreover, those who are not have the least money and if they charge 50 euros for a Moderna vaccine and 42 for Pfizer, the majority of people in the world cannot be vaccinated. In addition, the technical problems of maintaining minus eighty degrees must be taken into account,” says Larraga.

In this sense, the scientist considers that the The solution is to develop other cheap vaccines without technical specifications. “Mine is one of them,” says Larraga, who points out that you can’t cross the jungle with a fridge at minus eighty degrees. “We need a vaccine that lasts two months at room temperature. If it is reached, it can be sent and distributed by the least developed countries”.

For his part, Zuñiga considers “Inevitable cases” that as long as there is no vaccination coverage in the world, the virus “will continue to working with great force and generating new variants”. “Furthermore, where rates are high, non-pharmacological measures have been withdrawn, generating many transmissions and for each infection the virus has the opportunity to mutate. At the moment, it is inevitable that this will continue to change and that ‘There continue to be reinfections and epidemics from time to time,’ laments the virologist.

Although it may contain statements, data, or notes from healthcare institutions or professionals, the information in Medical Writing is edited and prepared by journalists. We recommend that the reader consult a healthcare practitioner with any health-related questions.

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